Hypericin content of Nova Scotia biotypes of Hypericum perforatum L.

effects of hot air drying method on hypericin extracted content of hypericum perforatum l. leaves.

drying is considered as one of the important stages after plant harvesting which plays an important role in maintaining the quantity and quality of their active ingredients. st. john's wort (hypericum perforatum l.) is an important medicinal plant that high percentages of hypericin in its leaves and flowers are considered as the most important feature of the iranian species. in this resear...

The Biological Activities of Hypericum Perforatum L.

BACKGROUND Mastitis reduces milk yield and alters milk composition. Antibiotics are widely used in the treatment of the disease. However, this widespread use of antibiotics causes both antibiotic residues in milks and antibiotic resistance developed in bacteria. Today's researches are focused on discovering and using new antibiotics against bacteria. OBJECTIVE The aim of this work was to disc...

St John's Wort (Hypericum perforatum L.) Photomedicine: Hypericin-Photodynamic Therapy Induces Metastatic Melanoma Cell Death

Hypericin, an extract from St John's Wort (Hypericum perforatum L.), is a promising photosensitizer in the context of clinical photodynamic therapy due to its excellent photosensitizing properties and tumoritropic characteristics. Hypericin-PDT induced cytotoxicity elicits tumor cell death by various mechanisms including apoptosis, necrosis and autophagy-related cell death. However, limited rep...

Effect of time of harvest on hypericin and essential oil content of hypericum performatum L.

Preparation of a polyclonal antibody against hypericin synthase and localization of the enzyme in red-pigmented Hypericum perforatum L. plantlets.

Hypericum perforatum is well known for its antidepressant and anti-inflammatory activities, for which hypericin and its derivatives are indicated to be the most active compounds. Hypericin synthase (Hyp-1) is the only protein proven to catalyze the synthesis of hypericin. In this study, the full-length cDNA of Hyp-1 was chemically synthesized according to the Hyp-1 sequence in GenBank (accessio...